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A.E. Arbuzov Institute of Organic and Physical Chemistry

Kazan Scientific Centre Russian Academy of Sciences

The International Arbuzov Award in the field of organophosphorous chemistry

July 11, 1997, on the eve of the 120th anniversary of academician Alexander Е. Arbuzov, outstanding chemist, the Creator of a new branch of chemistry - chemistry of organophosphorus compounds, President of Tatarstan Mintimer Shaimiev signed a Decree on the establishment of the International Arbuzov Award in the field of organophosphorus chemistry.

2011

 

Georgr Michael Blackburn
(United Kingdom) (1935)

Professor of Chemical Biology of the University of Sheffield


Michael Blackburn has graduated University of Cambridge as Rockefeller Research Fellow in 1956. He performed his investigations under the supervision of Professor Lord Todd, Nobel Laureate. The biggest part of his scientific career is connected with University of Sheffield.
Considerable contribution into bioorganic chemistry, phosphorus chemistry, physical-organic chemistry, and basic enzymology made by Michael Blackburn cannot be overestimated. His most important achievements are closely connected with investigations of mechanism of enzyme-catalysed phosphoryl transfer, especially phosphatases and kinases. He designed non-hydrolysable nucleotide analogues incorporating various substituted bisphosphonates and trisphosphonates for studies on DNA repair enzymes and AdoMet processes including histone methylation. His investigations in the field of catalytic antibodies - from mechanism to cancer chemotherapy, are pioneer works.Professor Blackburn initiated research of phosphatase using selection technology as well studies with synthetic analogues of rare adenosine nucleotides - especially for cell-signalling. Now he is actively working in the area of enzyme inhibitors chemistry, especially for carbonic anhydrase and glaucoma therapy.
Prof. Blackburn is author of over 270 research papers in learned journals and three books as well the author and co-author of some 12 patents on bisphosphonates, on drug development for histone methylase inhibitors, on topical treatment of glaucoma, and on drug developments for avian influenza neuraminidase.
He is the member of many prestigious international scientific organizations as well the member of editorial boards of some scientific journals.